Buy Retatrutide GLP1R – GLP3
Choose Standard Batch for stable inventory or Fresh Microbatch for recent small-run production, finalized within the last 1–3 weeks to preserve maximum available peptide content – never warehouse stock.
Buy Retatrutide (LY3437943) Research Peptide – Triple Agonist Vials for Sale
BulkGLP1R is a dedicated U.S. supplier of high-purity Retatrutide for sale to qualified laboratories. We specialize in providing the LY3437943 **triple-agonist peptide** as a **mannitol-free**, lyophilized research chemical. All formats are third-party tested to $\ge$99% purity (HPLC/MS) to ensure reliable, repeatable results for your in-vitro studies.
Laboratory Research Use Only. Not for human or veterinary use. No clinical, diagnostic, or therapeutic claims are made or implied.
Available Research Grades & Batch Formats
We offer two distinct grades of Retatrutide to meet specific lab requirements for freshness, value, and batch consistency.
Standard Research Batch
- $\ge$99% purity (HPLC/MS) – COA on page
- Cold-stored for stability and planning simplicity
- Singles **and** 10-packs (lot-consistent where possible) for method development
- Best value for routine, repeatable research workflows
Fresh Microbatch Retatrutide: (Premium)
- Purity Verified: Manufactured and lab-certified within the last 3 weeks, ensuring the highest level of **freshness, integrity, and potency**.
- Superior Chain-of-Custody: Optimized, rapid supply chain with enhanced handling protocols to maintain **molecular stability** from synthesis to your lab.
- Exclusive Availability: Controlled, small-run batches (singles only)
- Full Transparency: Dedicated **Certificate of Analysis (COA)**
Pricing note: Fresh Microbatch reflects a premium tier due to limited release volume, small-run handling, and shorter time-to-finalization. Standard Batch retains identical analytical specifications and remains the best value for routine studies.
Quality & Purity Guarantee (Why Choose BulkGLP1R)
- Analytical Grade: $\ge$99% purity verified by third-party HPLC/MS
- Mannitol-Free: 100% pure lyophilized peptide. No bulking agents, buffers, or excipients that could interfere with research data.
- Two Batch Formats: Choose **Standard Batch** (value, bulk packs) or **Fresh Microbatch** (premium, recent synthesis).
- Lot Consistency: Standard 10-packs are drawn from the same controlled lot, crucial for reproducible longitudinal studies.
- U.S. Fulfillment: Fast, discreet, and trackable shipments from within the United States.
What Is Retatrutide (LY3437943)?
Retatrutide (LY3437943), informally known in research communities as the "GLP-3 peptide," is a novel triple-agonist peptide. It is designed to concurrently engage three critical metabolic receptors (GLP-1, GIP, and glucagon), making it a significant subject of research for its potential synergistic effects on metabolic pathways.
Its unique mechanism of action combines three signaling pathways into a single molecule:
- GLP-1 Receptor Axis: Studied for its role in satiety signaling, delayed gastric emptying, and managing body-weight endpoints.
- GIP Receptor Axis: Investigated for potentiating glucose-dependent insulin secretion and its role in lipid metabolism.
- Glucagon Receptor Axis: The key differentiator. This axis is researched for promoting lipolysis (fat breakdown) and increasing thermogenic/energy-expenditure signals.
Supplied for in-vitro/ex-vivo research by qualified laboratories; not for administration to humans or animals.
Research Evidence Snapshot
Published reports (preclinical and Phase 2) have described notable body-weight endpoints and metabolic markers with triple-agonist designs compared with single/dual incretin approaches, alongside tolerability profiles consistent with incretin-pathway agents. Teams should review the primary literature for detailed methods, inclusion criteria, titration paradigms, and endpoint definitions.
Retatrutide vs Tirzepatide vs Semaglutide
| Feature | Retatrutide (Tri-Agonist) | Tirzepatide (Dual-Agonist) | Semaglutide (Single-Agonist) |
|---|---|---|---|
| Agonism | Triple: GLP-1, GIP, Glucagon | Dual: GLP-1, GIP | Single: GLP-1 |
| Primary Research Focus | Combined energy expenditure, appetite & glycemic pathways | Incretin synergy; appetite & glycemic control | Satiety signaling & glycemic control |
| Key Differentiator | Includes Glucagon receptor for lipolysis/thermogenic research | Combines two incretin pathways | Well-characterized GLP-1 profile |
Reconstitution & Storage Protocol
- Form: Lyophilized (freeze-dried) powder in sealed, sterile research vials.
- Fill Amounts: 10 mg, 15 mg, 20 mg, 30 mg per vial.
- Reconstitution Solvent: The standard diluent for most research protocols is Bacteriostatic Water (BAC Water). Introduce the solvent slowly down the side of the vial.
- Mixing: Gently swirl or roll the vial. Do not shake vigorously, as this can denature the peptide structure.
- Calculator: Use the Peptide Reconstitution Calculator to derive mg/mL targets and aliquot volumes.
- Storage (Unreconstituted): For long-term stability, store lyophilized powder at -20°C, protected from light.
- Storage (Reconstituted): Store reconstituted solution at 2–8 °C. Aliquot into smaller vessels to minimize freeze–thaw cycles.
Product Specifications
- Name: Retatrutide
- Synonyms: LY3437943, "GLP-3 Peptide"
- Purity: $\ge$99% (Verified by Third-Party HPLC/MS)
- Appearance: White/off-white lyophilized powder
- Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
- Molecular Weight: ~4,731.33 g/mol
- Additives: None. **Mannitol-free** and contains no buffers or excipients.
- Intended Use: In-vitro/ex-vivo laboratory research only.
- CAS Number: 2381089-83-2
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Retatrutide Resources
- What Is Retatrutide? Mechanism & Research Overview
- Retatrutide vs Tirzepatide – Research Comparison
- Is Retatrutide Legal to Buy for Research?
- Compare with Semaglutide (GLP-1)
- Compare with Tirzepatide (GLP-1/GIP)
- Wholesale & Custom Fills
Frequently Asked Questions
Where can I buy high-purity Retatrutide for research?
High-purity ($\ge$99%) Retatrutide for sale online should only be sourced from reputable suppliers who provide third-party verification. BulkGLP1R specializes in analytical-grade, mannitol-free Retatrutide for laboratory use and provides a current Certificate of Analysis (COA) on this page.
What is the difference between Retatrutide vs Tirzepatide?
The main difference is their mechanism. Tirzepatide is a **dual-agonist** (GLP-1 and GIP). Retatrutide is a **triple-agonist** (GLP-1, GIP, and Glucagon). The addition of the Glucagon receptor axis is the key differentiator, studied for its unique effects on energy expenditure and lipolysis (fat breakdown).
Is Retatrutide the “GLP-3” peptide?
Yes, “GLP-3” is an informal shorthand used online to describe Retatrutide (LY3437943). The more precise technical term is a "tri-agonist" or "triple-agonist peptide" because it targets three receptors (GLP-1, GIP, Glucagon).
What is the best solvent for Retatrutide reconstitution?
The standard, recommended solvent for reconstituting Retatrutide and other lyophilized peptides for research is Bacteriostatic Water (BAC Water). This sterile water contains 0.9% benzyl alcohol as a preservative, allowing for multiple withdrawals from the same vial while maintaining sterility. Always follow your specific lab protocol.
What is “Fresh Microbatch” Retatrutide?
This is our premium-tier format for labs requiring the absolute highest integrity. "Fresh Microbatch" vials are manufactured and lab-certified ( $\ge$99% purity) within the last 3 weeks, ensuring maximum potency and minimal time in storage. This format is ideal for highly sensitive assays.
Legal & Safety
All products are supplied for laboratory research use only. Not for human or veterinary administration. End users are responsible for compliance with applicable laws and institutional policies. By purchasing, you acknowledge these terms.
Additional information
| Weight | 0.1 lbs |
|---|---|
| Dimensions | 2 × 2 × 2 in |
| Size | 5mg, 10mg, 15mg, 20mg, 30mg, 5mg – 10 Pack, 10mg – 10 Pack, 15mg – 10 Pack, 20mg – 10 Pack, 30mg – 10 Pack |
| Product Grade | Standard Batch, Fresh Microbatch (Recommended) 🔥 |
2 reviews for Buy Retatrutide GLP1R - GLP3
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Katy –
Observations in my research have been impressive so far. The compound appears to strongly influence appetite-related pathways and significantly reduce cravings in testing environments, even during periods when cravings are typically elevated. After about 30 days of consistent research, measurable progress was recorded. Very satisfied with the quality and purity of this Retatutrid and will continue future research.
Raptor14 –
Excellent quality compound. Unlike others I’ve tested, this one delivers consistent results without any unexpected issues during research. Very satisfied with the purity and overall experience will continue future research projects with this supplier.